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Contents Volume II Issue I ( 2017)

 
Role of Computer Aided Drug Design in Modern Drug Discovery and Pharmacokinetic Prediction
Abstract:  In modern day, Data on different diseases and drug substances with their properties like modification, side effects, and dose requires documentation data and building library exploring, such library with vast information in every aspect needs computational methods used in CADD. Recognition of specific targets for the drug tested and defining pharmacological activity of a drug candidate based o ...Read More - Download PDF - View Fulltext
Author/s: 1-Arif Paiman
Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

2-Ahmad Mohammad
Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan

3-Mubashar Rehman
Assistant Professor, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

Keywords:Computer Aided Drug Design, Pharmacokinetics, Computational Methods, Drug Discovery, Novel Drug Candidate, Target -Drug Interaction
DOI Number:10.31703/gdddr.2017(II-I).01 DOI Link:http://dx.doi.org/10.31703/gdddr.2017(II-I).01
Page Nos:1-8 Volume & Issue:II-I
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A Review of Parenteral Administration of Testing Substance in Rabbit and Mice
Abstract:  There are many publications that deal with administration of test substances to animals and removal of blood samples for different objectives. Parenteral route of drug administration includes further different routes i.e., drug administration through muscles (IM route) through veins (IV route) and through subcutaneous route. We can manage to check the outcomes of test substances within minutes ...Read More - Download PDF - View Fulltext
Author/s: 1-Muhammad Shehzeb Ashraf
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan

2-Iqra Rehman
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan

3-Gul Shahnaz
Chairperson, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

Keywords:Intramuscular, Anesthesia, Doses, Administration, Mice, Subcutaneous, Parenteral
DOI Number:10.31703/gdddr.2017(II-I).02 DOI Link:http://dx.doi.org/10.31703/gdddr.2017(II-I).02
Page Nos:9-17 Volume & Issue:II-I
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A Literature Review of the Physicochemical, Physiological and Pharmaceutical Considerations in GIT Absorption of Drugs.
Abstract:  Oral route of drug administration is the most common among all routes and hence their pharmacokinetic and pharmacodynamic factors are substantial to study. Among such factors, GIT absorption is the key factor in new drug development affecting the efficacy as well as safety of the drug. Different protocols have now been developed for the usage of in vitro also the in vivo as well as in situ met ...Read More - Download PDF - View Fulltext
Author/s: 1-Rabia Mazhar
Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.

2-Fariah Qaiser
Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.

3-Sana Ali Zahra
Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.

4-Syeda Komal Fatima
Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.

5-Imran Khan
Associate Professor, Riphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore Campus, Lahore, Punjab, Pakistan.
Keywords:Absorption, Gastro-Intestinal Tract, Transport, Bioavailability, Drug Dissolution, Diffusion, Drug Stability
DOI Number:10.31703/gdddr.2017(II-I).03 DOI Link:http://dx.doi.org/10.31703/gdddr.2017(II-I).03
Page Nos:18-33 Volume & Issue:II-I
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Strategies and Techniques of Drug Discovery from Natural Products
Abstract:  New drugs are mostly obtained from Natural sources. The traditional and ethic medicines have provided evidence on the therapeutic properties and resulted in some distinguished drug discovery of natural products. The microorganisms and the endogenous active materials from human or animal have also become a significant approach to the discovery of a drug. Bioinformatics and artificial intelligen ...Read More - Download PDF - View Fulltext
Author/s: 1-Parniya Akbar Ali
Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.

2-Farah Hanif
Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.

3-Hosna Nettour
Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.

4-Mubashar Rehman
Assistant Professor, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

Keywords:Essential Products, Drug Development and Design, Discovery, Strategies, Omics.
DOI Number:10.31703/gdddr.2017(II-I).04 DOI Link:http://dx.doi.org/10.31703/gdddr.2017(II-I).04
Page Nos:34-43 Volume & Issue:II-I
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A Literature Study of IPQC (In Process Quality Control) tests and FDF (Finished Dosage Form) tests for Parenteral Dosage forms taking Adicovil IV Ampoule as an Example.
Abstract:  This study was conducted to evaluate both the in-process quality control tests as well as the finished dosage form tests for a parenteral product. Furthermore, all the processes from the purchase of API to marketing of product were studied. A batch of Adicovil was taken Adicovil was taken as an example, it is small volume parenteral of 2ml ampoule that is studied to evaluate its efficacy and s ...Read More - Download PDF - View Fulltext
Author/s: 1-Ayesha Sabir
Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.

2-Syeda Komal Fatima
Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.

3-Asma Kaleem
Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.

4-Sidra Altaf
Undergraduate Students, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.

5-Imran Khan
Associate Professor, Riphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore Campus, Lahore, Punjab, Pakistan.
Keywords:Parenteral, IPQC, stability tests, FDF, physical tests, chemical tests.
DOI Number:10.31703/gdddr.2017(II-I).05 DOI Link:http://dx.doi.org/10.31703/gdddr.2017(II-I).05
Page Nos:44-55 Volume & Issue:II-I
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Volumes

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Authors

75

Issue

5

Articles

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