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Contents Volume I Issue I ( 2016)

 
An Insight About the Drug Release Mechanisms from Different Dosage Forms
Abstract:  A process in which drug comes out from drug product and exposed to ADME and finally become accessible for pharmacological activity is known as drug release and mechanism involves the study of its rate and factors influencing its rate. Factors influencing the rate of drug release are drug related, polymer related and formulation variables. Drug delivery systems are discriminated on the basis of ...Read More - Download PDF - View Fulltext
Author/s: 1-Hafsa Shahid
a Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

2-Ayesha Ahmed
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

3-Ammarah Ashraf
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

4-Nida Rashid
d Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

5-Mubashir Rehman
Assistant Professor, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
Keywords:Drug Release Mechanisms, Dosage Forms, Drugs, Parenteral, Diffusion
DOI Number:10.31703/gdddr.2016(I-I).01 DOI Link:http://dx.doi.org/10.31703/gdddr.2016(I-I).01
Page Nos:1-8 Volume & Issue:I-I
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Pharmacokinetic Modeling Concepts: Compartmental and Non-compartmental approach for Drug Designing
Abstract:  Pharmacokinetic modeling helps to estimate the ADME parameters of all the natural and synthetic drug substances in humans and animals. There are two types of approaches for predicting the kinetic processes inside the body i.e., model approach and model independent approach. Model approach is further divided into compartmental and physiological models and model independent approach consists of ...Read More - Download PDF - View Fulltext
Author/s: 1-Duaa Aslam Chaudhry
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

2-Urooj Fatima
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

3-Kainat Waqar
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

4-Mubashar Rehman
Assistant Professor, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

Keywords: Pharmacokinetic, Models, Compartments, Parameters, Drug, Concentration
DOI Number:10.31703/gdddr.2016(I-I).02 DOI Link:http://dx.doi.org/10.31703/gdddr.2016(I-I).02
Page Nos:9-18 Volume & Issue:I-I
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Oral Drug Delivery to the Experimental Animals, A Mini Review
Abstract:  In several pharmacologic, pharmacology, and alternative medicine studies, oral administration of medication or test substances to experimental animals is needed. It is clinically sound and recommended to administer test substances to experimental animals along the same route that they are taken or expected to be taken by humans as general bioavailability; the pharmacology and pharmacology para ...Read More - Download PDF - View Fulltext
Author/s: 1-Arif Paiman
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

2-Ahmad Mohammadi
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

3-Rafia Inam
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

4-Aqsa Ameen
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

5-Mubashar Rehman
Assistant Professor, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
Keywords:Oral Administration, Experimental Animal, Cannula
DOI Number:10.31703/gdddr.2016(I-I).03 DOI Link:http://dx.doi.org/10.31703/gdddr.2016(I-I).03
Page Nos:19-26 Volume & Issue:I-I
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A Comprehensive Insight on Pharmacokinetics
Abstract:  Pharmacokinetics can be defined as what the body does to a drug. The basic parameters of pharmacokinetics are discussed here including absorption, distribution, metabolism, and excretion. Characteristics and pathways taken by these drugs are determined by these parameters. The mechanism followed by these parameters are also discussed. Furthermore, the factors affecting these parameters includi ...Read More - Download PDF - View Fulltext
Author/s: 1-Urooj Naseem
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

2-Fatima Iqbal
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

3-Gul Shahnaz
Chairperson, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

Keywords:Pharmacokinetics, Absorption, Distribution, Metabolism
DOI Number:10.31703/gdddr.2016(I-I).04 DOI Link:http://dx.doi.org/10.31703/gdddr.2016(I-I).04
Page Nos:27-37 Volume & Issue:I-I
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Statistical Moment Theory and Non-Compartmental Analysis
Abstract:  Mathematical model a numerical classification of the biological framework and utilized to state quantitative connections. A pharmacokinetic compartment is a numerical idea that portrays a space in the body that medication seems to possess These models just mediate the test information and permit an experimental equation for the assessment of medication focus with time. A non- compartmental m ...Read More - Download PDF - View Fulltext
Author/s: 1-Samina Zehussain
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

2-Muhammad Ilyas
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

3-Abdullah
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

4-Mubashar Rehman
Assistant Professor, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

Keywords:Non-Compartmental Model, the Non-Compartmental Analysis Statistical Moment Theory, the Non-Compartmental Analysis, Types of Models
DOI Number:10.31703/gdddr.2016(I-I).05 DOI Link:http://dx.doi.org/10.31703/gdddr.2016(I-I).05
Page Nos:38-48 Volume & Issue:I-I
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