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Translational Medicine and Drug Discovery: A Mini Review

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Abstract

There are a very large number of drugs that enter in the clinical trial phase but only a fraction of them is able to get their place in market. For a drug to reach at a phase of clinical trial requires a huge effort of research and a very large investment. Translational medicine, a relatively new discipline, uses the novel techniques that not only lower the risk of investment failure, but also focuses on reducing the testing duration in different phases of clinical trials. Discussed in the article are advantages of translational medicines and various challenges faced by translational medicine as well the ways by which this discipline will face these challenges. This article also focuses on recent advances in therapeutic development for diabetes, bone disorders, neurosciences, and oncology and the failures of translational medicine due to high external risk factors.

Authors

1-Muhammad Saadullah Khan
Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

2-Farwa Shahid
Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

3-Arooj Shahid
Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

4-Gul Shahnaz
Chairperson, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

Keywords

Clinical Trials, Biomarkers, Alzheimer’s, Fucoidin, Preclinical Modes, Bone Disorders

DOI Number

10.31703/gdddr.2018(III-I).02


Page Nos

6-15

Volume & Issue

III - I

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Published: Dec 2018

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