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Individualization of Dosage Regimen-an Approach Towards Improved Clinical Outcomes

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Abstract

Dosage regimen plays the most important role in obtaining the desired therapeutic outcomes. The focus perpetually is on the design of doses, their intervals and duration to acquire the optimum response. Many factors like age, gender, weight, body surface area, pathological state play a role in formulating these regimens and each factor is given importance in deciding regimen that gives the optimum response. The experiments gradually reveal the correct regimens after repeatedly being worked upon. Different parameters such as Cmax, Tmax, are calculated and estimated in order to decide by which dose and its interval the therapeutic level is maintained in the blood. Therapeutic drug monitoring is one of the most important aspects in dosage regimen where the narrow therapeutic index drugs are given and designed in such a way as to get the therapeutic response with minimized toxicity.

Authors

1-Syed Faaez Ul Hassan Naqvi
Undergraduate Students (Final Year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

2-Tehreem Haider
Undergraduate Students (Final Year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

Keywords

Dosage Regimen, Therapeutic Drug Monitoring, Multiple Dosage Regimen

DOI Number

10.31703/gdddr.2018(III-I).03


Page Nos

16-22

Volume & Issue

III - I

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Published: Dec 2018

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