Multiple Malignancies in Relation to Vitamin D Levels Among Women of Reproductive Age
The global burden of cancer, with deaths projected to increase from 7.6 million to 13.1 million by 2030, calls for urgent research into potential mitigating factors, such as Vitamin D levels. This study specifically addresses the correlation between Vitamin D and cancer prevalence among women of reproductive age, scrutinizing variables like age, socioeconomic background, and geographic location. Conducted at Fauji Foundation Hospital's Oncology department through detailed questionnaires, the study analyzes Vitamin D levels in newly diagnosed female cancer patients. While a significant direct association with cancer occurrence was not established, an alarming rate of Vitamin D deficiency and high obesity risk were noted. Furthermore, the study indicates an inverse relation between Vitamin D levels, sun exposure, and certain patient demographics. These findings underscore the necessity of considering environmental and lifestyle factors in cancer prevention strategies.
-
Malignancy, Reproductive age, Vitamin D levels, Prevention, Apoptosis, Prognosis
-
(1) Rashida Naseer
Medical Officer in Charge (MOIC), Oncology Ward, Department of Oncology, Fauji Foundation Hospital Rawalpindi, Punjab, Pakistan.
(2) Naseer Haider Cheema
Research Scholar, Information Systems, Riphah Institute of System Engineering, Islamabad, Pakistan.
(3) Quratulain Ikram
Medical Officer in Charge (MOIC), Gyne Ward, Citymed Hospital, Rawalpindi, Punjab, Pakistan.
- Giammanco, M., Di Majo, D., La Guardia, M., Aiello, S., Crescimannno, M., Flandina, C., Tumminello, F. M., & Leto, G. (2015). Vitamin D in cancer chemoprevention. Pharmaceutical Biology, 53(10), 1399–1434. https://doi.org/10.3109/13880209.2014.988 274
- Heald, F. A. (2023). Promoting Cardiac Rehabilitation Use Across the Phases: Focus on Women.
- Jeon, S., & Shin, E. (2018). Exploring vitamin D metabolism and function in cancer. Experimental and Molecular Medicine/Experimental and Molecular Medicine, 50(4), 1–14. https://doi.org/10.1038/s12276-018-0038-9
- Khan, I., Jawaid, A., Ahmad, K., & Noordin, S. (2015). Hip fragility fractures: Anaemia, calcium and vitamin D supplementation. PubMed, 65(11 Suppl 3), S55-8. https://pubmed.ncbi.nlm.nih.gov/26878537
- Miller, K. M., Hart, P., De Klerk, N., Davis, E. A., & Lucas, R. (2017). Are low sun exposure and/or vitamin D risk factors for type 1 diabetes? Photochemical & Photobiological Sciences, 16(3), 381–398. https://doi.org/10.1039/c6pp00294c
- Nguyen, S. M., Deppen, S. A., Nguyen, G. H., Pham, D. X., Bui, T. D., & Tran, T. A. (2019). Projecting cancer incidence for 2025 in the 2 largest populated cities in Vietnam. Cancer Control, 26(1), 107327481986527. https://doi.org/10.1177/1073274819865274
- Ogawa, S., Sato, J., Tanaka, R., Sakakibara, T., & Shino, M. (2022). Hyponatremia timing, incidence, and associated risk factors in patients treated with cisplatin for lung cancer: a retrospective study. Journal of Population Therapeutics and Clinical Pharmacology, 29(4). https://doi.org/10.47750/jptcp.2022.907
- Rickard, B. P., Conrad, C., Sorrin, A. J., Ruhi, M. K., Reader, J., Huang, S., Franco, W., Scarcelli, G., Polacheck, W. J., Roque, D. M., Del Carmen, M. G., Huang, H., Demirci, U., & Rizvi, I. (2021). Malignant ascites in ovarian cancer: cellular, acellular, and biophysical determinants of molecular characteristics and therapy response. Cancers, 13(17), 4318. https://doi.org/10.3390/cancers13174318
- Saeed, S., Khan, J., Iqbal, N., Irfan, S., Shafique, A., & Awan, S. (2019). Cancer and how the patients see it; prevalence and perception of risk factors: a cross-sectional survey from a tertiary care centre of Karachi, Pakistan. BMC Public Health, 19(1). https://doi.org/10.1186/s12889-019-6667-7
- Safari, H., Eftekhari, M. H., Zadeh, J. H., & Dashtabi, A. (2017). Prevalence of vitamin D deficiency and its relationship with metabolic syndrome markers and lifestyle in the adult population in a sunny tropical region. DOAJ (DOAJ: Directory of Open Access Journals). https://doaj.org/article/84f4a5ed3238441f9abf1a8c1d70c013
- Stade, B., Ali, A. I., Bennett, D., Campbell, D., Johnston, M., Lens, C., Tran, S., & Koren, G. (2009). The burden of prenatal exposure to alcohol: revised measurement of cost. PubMed, 16(1), e91-102. https://pubmed.ncbi.nlm.nih.gov/19168935
- Ullah, F., Nadeem, M., Abrar, M., Amin, F., Salam, A., Alabrah, A., & AlSalman, H. (2023). Evolutionary Model for Brain Cancer-Grading and Classification. IEEE Access, 11, 126182–126194. https://doi.org/10.1109/access.2023.3330919
- Ullah, F., Nadeem, M., Abrar, M., Amin, F., Salam, A., & Khan, S. (2023). Enhancing Brain Tumor Segmentation Accuracy through Scalable Federated Learning with Advanced Data Privacy and Security Measures. Mathematics, 11(19), 4189. https://doi.org/10.3390/math11194189
- VITAMIN, D. (2008). Eighth European Congress on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis – ECCEO 8. (2008b). Osteoporosis International, 19(S1), 1–4. https://doi.org/10.1007/s00198- 008-0567
Cite this article
-
APA : Naseer, R., Cheema, N. H., & Ikram, Q. (2023). Multiple Malignancies in Relation to Vitamin D Levels Among Women of Reproductive Age. Global Drug Design & Development Review, VIII(IV), 34-45. https://doi.org/10.31703/gdddr.2023(VIII-IV).04
-
CHICAGO : Naseer, Rashida, Naseer Haider Cheema, and Quratulain Ikram. 2023. "Multiple Malignancies in Relation to Vitamin D Levels Among Women of Reproductive Age." Global Drug Design & Development Review, VIII (IV): 34-45 doi: 10.31703/gdddr.2023(VIII-IV).04
-
HARVARD : NASEER, R., CHEEMA, N. H. & IKRAM, Q. 2023. Multiple Malignancies in Relation to Vitamin D Levels Among Women of Reproductive Age. Global Drug Design & Development Review, VIII, 34-45.
-
MHRA : Naseer, Rashida, Naseer Haider Cheema, and Quratulain Ikram. 2023. "Multiple Malignancies in Relation to Vitamin D Levels Among Women of Reproductive Age." Global Drug Design & Development Review, VIII: 34-45
-
MLA : Naseer, Rashida, Naseer Haider Cheema, and Quratulain Ikram. "Multiple Malignancies in Relation to Vitamin D Levels Among Women of Reproductive Age." Global Drug Design & Development Review, VIII.IV (2023): 34-45 Print.
-
OXFORD : Naseer, Rashida, Cheema, Naseer Haider, and Ikram, Quratulain (2023), "Multiple Malignancies in Relation to Vitamin D Levels Among Women of Reproductive Age", Global Drug Design & Development Review, VIII (IV), 34-45
-
TURABIAN : Naseer, Rashida, Naseer Haider Cheema, and Quratulain Ikram. "Multiple Malignancies in Relation to Vitamin D Levels Among Women of Reproductive Age." Global Drug Design & Development Review VIII, no. IV (2023): 34-45. https://doi.org/10.31703/gdddr.2023(VIII-IV).04