Despite the advancement in prevention and treatment against infection, osteomyelitis has always remained a challenge for an orthopedic surgeon. Although this problem is more prevalent in developing countries rather than developed countries, still it cannot be overlooked. That's why we have aimed this case study to consider the therapeutic plan and techniques used for the treatment of osteomyelitis. A 67 years old male was presented in a local public hospital of Islamabad, Pakistan with severe pain in right lateral thigh unable to move hip and knee joint and swelling. Emergency treatment included diclofenac. X-rays result showed fracture of right femur. Cultures DHS fixation (Dynamic Hip Screw fixation) was done, pus was drained and culture reports indicated Staphylococcus areas that was sensitive to Cefotaxime. The therapy plan included antibiotics along with pain killers, but the infection was not treated. Beside x-ray. Finally this infection was treated using antibiotics beading technique.