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Oral Drug Delivery to the Experimental Animals, A Mini Review

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Abstract

In several pharmacologic, pharmacology, and alternative medicine studies, oral administration of medication or test substances to experimental animals is needed. It is clinically sound and recommended to administer test substances to experimental animals along the same route that they are taken or expected to be taken by humans as general bioavailability; the pharmacology and pharmacology parameters obtained for the drug will depend significantly on the route chosen to administer it. The lack of ready access to high-quality oral tubing built for different species, as well as a widespread lack of technical expertise to properly use out-of-the-box techniques in this part of the world, has made this route controversial among medicine scientists. The typical problems and difficulties associated with the oral administration of test product solutions were avoided by mistreating either the syringe alone or incorporating it into the animals feeds or drinkables. This jury-rigged oral tubing was also used to ensure that the expected doses were correctly administered in each case.

Authors

1-Arif Paiman
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

2-Ahmad Mohammadi
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

3-Rafia Inam
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

4-Aqsa Ameen
Undergraduate Students (Final year), Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

5-Mubashar Rehman
Assistant Professor, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

Keywords

Oral Administration, Experimental Animal, Cannula

DOI Number

10.31703/gdddr.2016(I-I).03


Page Nos

19-26

Volume & Issue

I - I

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Published: Dec 2016

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