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DESIGN OF HOLLOW NANOCAPSULES AND THEIR APPLICATIONS IN BIOMEDICAL IMAGING

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02 Pages : 15-24

http://dx.doi.org/10.31703/gdddr.2020(V-I).02      10.31703/gdddr.2020(V-I).02      Published : Dec 2020

Design of Hollow Nanocapsules and their Applications in Biomedical Imaging

Abstract

    Different nanocarrier systems owing to their nano size, increased surface area and unique electrical and magnetic properties are employed for biomedical applications. Among the various nanocarrier systems, hollow nanocapsules are one of the most interesting carrier systems for thier use in bioimaging and biomedical applications. The unique properties of hollow nanocapsules make them suitable for use in bioimaging. In this article hollow nanocpsules have been classified into four classes based on thier composition: (i) liposomes, (ii) polmersomes and other polymeric hollow nanocapsules, (iii) metallic hollow nanocapsules and (iv) others. The formation and design of these hollow nanocapsules and their diagnostic and therapeutic applications using different agents/imaging probes and imaging modalities is discussed briefly. Hollow nanocapsules have revolutionized the field of biomedical imaging.

    Biomedical Applications, Bioimaging, Hollow Nanocapsules, Imaging Probes, Nanocarriers

    (1) Aimen Qaiser
    MPhil Candidate, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (2) Muhammad Rauf ul Hassan
    Associate Professor, Department of Pulmonology, Quaid-i-Azam Medical College, Bahawalpur Victoria Hospital, Bahawalpur, Punjab, Pakistan.
    (3) Maria Hassan Kiani
    PhD Candidate, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (4) Husna Khalid
    MPhil Candidate, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (5) Gul Shahnaz
    Chairperson/ Associate Professor, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
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References

  • Akbarzadeh, A., Rezaei-Sadabady, R., Davaran, S., Joo, S. W., Zarghami, N., Hanifehpour, Y., . . . Nejati-Koshki, K. (2013). Liposome: classification, preparation, and applications. Nanoscale research letters, 8(1), 102.
  • Fessi, H., Puisieux, F., Devissaguet, J. P., Ammoury, N., & Benita, S. (1989). Nanocapsule formation by interfacial polymer deposition following solvent displacement. International journal of pharmaceutics, 55(1), R1-R4.
  • Anton, N., Benoit, J.-P., & Saulnier, P. (2008). Design and production of nanoparticles formulated from nano-emulsion templates - a review. Journal of controlled release, 128(3), 185-199.
  • Ishizuka, F., Utama, R. H., Kim, S., Stenzel, M. H., & Zetterlund, P. B. (2015). RAFT inverse miniemulsion periphery polymerization in binary solvent mixtures for synthesis of nanocapsules. European Polymer Journal, 73, 324-334.
  • Ashjari, M., Khoee, S., & Mahdavian, A. R. (2012). Controlling the morphology and surface property of magnetic/cisplatin-loaded nanocapsules via W/O/W double emulsion method. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 408, 87-96.
  • Jang, W.-D., Yim, D., & Hwang, I.-H. (2014). Photofunctional hollow nanocapsules for biomedical applications. Journal of Materials Chemistry B, 2(16), 2202-2211.
  • Chen, Y., Chen, H., Zeng, D., Tian, Y., Chen, F., Feng, J., & Shi, J. (2010). Core/shell structured hollow mesoporous nanocapsules: a potential platform for simultaneous cell imaging and anticancer drug delivery. ACS nano, 4(10), 6001-6013.
  • Ledo, A. M., Sasso, M. S., Bronte, V., Marigo, I., Boyd, B. J., Garcia-Fuentes, M., & Alonso, M. J. (2019). Co-delivery of RNAi and chemokine by polyarginine nanocapsules enables the modulation of myeloid-derived suppressor cells. Journal of Controlled Release, 295, 60-73.
  • Cuomo, F., Lopez, F., Piludu, M., Miguel, M. G., Lindman, B., & Ceglie, A. (2015). Release of small hydrophilic molecules from polyelectrolyte capsules: Effect of the wall thickness. Journal of colloid and interface science, 447, 211-216.
  • Leong, J., Teo, J. Y., Aakalu, V. K., Yang, Y. Y., & Kong, H. (2018). Engineering polymersomes for diagnostics and therapy. Advanced healthcare materials, 7(8), 1701276.
  • Deng, S., Gigliobianco, M. R., Censi, R., & Di Martino, P. (2020). Polymeric Nanocapsules as Nanotechnological Alternative for Drug Delivery System: Current Status, Challenges and Opportunities. Nanomaterials, 10(5), 847.
  • Ma, J., Feng, P., Ye, C., Wang, Y., & Fan, Y. (2001). An improved interfacial coacervation technique to fabricate biodegradable nanocapsules of an aqueous peptide solution from polylactide and its block copolymers with poly (ethylene glycol). Colloid and Polymer Science, 279(4), 387- 392.
  • Dergunov, S. A., & Pinkhassik, E. (2014). Hollow Nanocapsules in Biomedical Imaging Applications. Nanotechnology for Biomedical Imaging and Diagnostics, 83- 109.
  • Meier, W. (2000). Polymer nanocapsules. Chemical Society Reviews, 29(5), 295-303.
  • Ferranti, V., Marchais, H., Chabenat, C., Orecchioni, A., & Lafont, O. (1999). Primidone-loaded poly-ε-caprolactone nanocapsules: incorporation efficiency and in vitro release profiles. International journal of pharmaceutics, 193(1), 107-111.
  • Rani, R., Sethi, K., & Singh, G. (2019). Nanomaterials and Their Applications in Bioimaging Plant Nanobionics (pp. 429-450): Springer.
  • Sadeghian, M., Akhlaghi, P., & Mesbahi, A. (2020). Investigation of imaging properties of novel contrast agents based on gold, silver and bismuth nanoparticles in spectral computed tomography using Monte Carlo simulation. Polish Journal of Medical Physics and Engineering, 26(1), 21-29.
  • Shang, B., Zhang, X., Ji, R., Wang, Y., Hu, H., Peng, B., & Deng, Z. (2020). Preparation of colloidal polydopamine/Au hollow spheres for enhanced ultrasound contrast imaging and photothermal therapy. Materials Science and Engineering: C, 106, 110174.
  • Zhang, Y., Chi, C., Huang, X., Zou, Q., Li, X., & Chen, L. (2017). Starch-based nanocapsules fabricated through layer-by-layer assembly for oral delivery of protein to lower gastrointestinal tract. Carbohydrate polymers, 171, 242-251.
  • Silindir, M., Erdoğan, S., Özer, A. Y., & Maia, S. (2012). Liposomes and their applications in molecular imaging. Journal of drug targeting, 20(5), 401-415.
  • Zhang, Y., García-Gabilondo, M., Grayston, A., Feiner, I. V., Anton-Sales, I., Loiola, R. A., . . . Garcia- Dorado, D. (2020). PLGA protein nanocarriers with tailor-made fluorescence/MRI/PET imaging modalities. Nanoscale, 12(8), 4988-5002.
  • Wang, J. T.-W., Martino, U., Khan, R., Bazzar, M., Southern, P., Tuncel, D., & Al-Jamal, K. T. (2020). Engineering red-emitting multi- functional nanocapsules for magnetic tumour targeting and imaging. Biomaterials Science, 8(9), 2590-2599.
  • Zhang, Y., Hsu, B. Y. W., Ren, C., Li, X., & Wang, J. (2015). Silica-based nanocapsules: synthesis, structure control and biomedical applications. Chemical Society Reviews, 44(1), 315-335.
  • Xia, Y., Xu, C., Zhang, X., Ning, P., Wang, Z., Tian, J., & Chen, X. (2019). Liposome-based probes for molecular imaging: from basic research to the bedside. Nanoscale, 11(13), 5822- 5838.

Cite this article

APA

    APA : Qaiser, A., Hassan, M. R. u., & Kiani, M. H. (2020). Design of Hollow Nanocapsules and their Applications in Biomedical Imaging. Global Drug Design & Development Review, V(I), 15-24. https://doi.org/10.31703/gdddr.2020(V-I).02

CHICAGO

    CHICAGO : Qaiser, Aimen, Muhammad Rauf ul Hassan, and Maria Hassan Kiani. 2020. "Design of Hollow Nanocapsules and their Applications in Biomedical Imaging." Global Drug Design & Development Review, V (I): 15-24 doi: 10.31703/gdddr.2020(V-I).02

HARVARD

    HARVARD : QAISER, A., HASSAN, M. R. U. & KIANI, M. H. 2020. Design of Hollow Nanocapsules and their Applications in Biomedical Imaging. Global Drug Design & Development Review, V, 15-24.

MHRA

    MHRA : Qaiser, Aimen, Muhammad Rauf ul Hassan, and Maria Hassan Kiani. 2020. "Design of Hollow Nanocapsules and their Applications in Biomedical Imaging." Global Drug Design & Development Review, V: 15-24

MLA

    MLA : Qaiser, Aimen, Muhammad Rauf ul Hassan, and Maria Hassan Kiani. "Design of Hollow Nanocapsules and their Applications in Biomedical Imaging." Global Drug Design & Development Review, V.I (2020): 15-24 Print.

OXFORD

    OXFORD : Qaiser, Aimen, Hassan, Muhammad Rauf ul, and Kiani, Maria Hassan (2020), "Design of Hollow Nanocapsules and their Applications in Biomedical Imaging", Global Drug Design & Development Review, V (I), 15-24

TURABIAN

    TURABIAN : Qaiser, Aimen, Muhammad Rauf ul Hassan, and Maria Hassan Kiani. "Design of Hollow Nanocapsules and their Applications in Biomedical Imaging." Global Drug Design & Development Review V, no. I (2020): 15-24. https://doi.org/10.31703/gdddr.2020(V-I).02