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ASSESSMENT OF VITAMIN D STATUS AND RESPONSE TO VITAMIN D3 IN OBESE AND NONOBESE CHILDREN AND ADULTS

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03 Pages : 15–21

http://dx.doi.org/10.31703/gdddr.2023(VIII-I).03      10.31703/gdddr.2023(VIII-I).03      Published : Mar 2023

Assessment of Vitamin D Status and Response to Vitamin D3 in Obese and Non-Obese Children and Adults

Abstract

    Due to its great prevalence and harmful consequences on health, obesity appears to be a serious problem in today's society. Studies have connected obesity with lower blood calcifediol concentrations. Examining the blood vitamin D levels among overweight and non-obese adults as well as adolescents was the goal of the current study, as well as compare how they responded to the similar oral vitamin D3 treatment. The blood vitamin D levels of a small number of obese children and adults and some obese individuals were compared in a non-randomized clinical study. 1 pearl of vitamin D3 (50 000 Iu) was given to those with a blood vitamin D status of thirty milligrams per milliliter (74 occurrences) every week for six weeks. Two weeks after starting therapy, serum vitamin D levels were tested once again. At baseline, individuals with obesity had a frequency of low Vit D level of 42/44 (95.5%) compared to 31/46 (66.6%) of patients with non- obesity (p 0.002). The aforementioned percentages were reduced to 24/43 (55.8%) and 1/30 (3.3%), respectively, following therapy for these individuals (p 0.001). Our investigation showed that patients, especially those who were obese, frequently had vitamin D deficiencies. Moreover, the obese group shows a modest therapeutic response.

    Vitamin D, Vitamin D3, Obese, Children, Adult

    (1) Muhammad Shoaib
    Assistant Professor, Department of Biochemistry, Gajju khan Medical College, Swabi, KP, Pakistan.
    (2) Mehreen Ismail
    Department of Biochemistry, Khyber Medical University, Peshawar, KP, Pakistan.
    (3) Mehak E Fatima
    Demonstrator, Department of Forensic Medicine, Rawal Institute of Health and Sciences, Islamabad, Pakistan.
    (4) Fazeelat Hajra Karim
    Lecturer, Department of Physiology, Khyber Girls Medical College, Peshawar, KP, Pakistan.
    (5) Shazia Muazam
    Associate Professor, Department of Anatomy, HBS Medical and Dental College, Islamabad, Pakistan.
    (6) Afshan Iftikhar
    Assistant Professor, Department of Physiology, Muhammad College of Medicine, Peshawar, KP, Pakistan.
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Cite this article

APA

    APA : Shoaib, M., Ismail, M., & Fatima, M. E. (2023). Assessment of Vitamin D Status and Response to Vitamin D3 in Obese and Non-Obese Children and Adults. Global Drug Design & Development Review, VIII(I), 15–21. https://doi.org/10.31703/gdddr.2023(VIII-I).03

CHICAGO

    CHICAGO : Shoaib, Muhammad, Mehreen Ismail, and Mehak E Fatima. 2023. "Assessment of Vitamin D Status and Response to Vitamin D3 in Obese and Non-Obese Children and Adults." Global Drug Design & Development Review, VIII (I): 15–21 doi: 10.31703/gdddr.2023(VIII-I).03

HARVARD

    HARVARD : SHOAIB, M., ISMAIL, M. & FATIMA, M. E. 2023. Assessment of Vitamin D Status and Response to Vitamin D3 in Obese and Non-Obese Children and Adults. Global Drug Design & Development Review, VIII, 15–21.

MHRA

    MHRA : Shoaib, Muhammad, Mehreen Ismail, and Mehak E Fatima. 2023. "Assessment of Vitamin D Status and Response to Vitamin D3 in Obese and Non-Obese Children and Adults." Global Drug Design & Development Review, VIII: 15–21

MLA

    MLA : Shoaib, Muhammad, Mehreen Ismail, and Mehak E Fatima. "Assessment of Vitamin D Status and Response to Vitamin D3 in Obese and Non-Obese Children and Adults." Global Drug Design & Development Review, VIII.I (2023): 15–21 Print.

OXFORD

    OXFORD : Shoaib, Muhammad, Ismail, Mehreen, and Fatima, Mehak E (2023), "Assessment of Vitamin D Status and Response to Vitamin D3 in Obese and Non-Obese Children and Adults", Global Drug Design & Development Review, VIII (I), 15–21

TURABIAN

    TURABIAN : Shoaib, Muhammad, Mehreen Ismail, and Mehak E Fatima. "Assessment of Vitamin D Status and Response to Vitamin D3 in Obese and Non-Obese Children and Adults." Global Drug Design & Development Review VIII, no. I (2023): 15–21. https://doi.org/10.31703/gdddr.2023(VIII-I).03