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BIOADHESIVE NANOMEDICINE FOR TARGETED DRUG DELIVERY

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02 Pages : 10-23

http://dx.doi.org/10.31703/gdddr.2019(IV-I).02      10.31703/gdddr.2019(IV-I).02      Published : Dec 2019

Bio-Adhesive Nanomedicine for Targeted Drug Delivery

Abstract

    The bio/muco-adhesive auxiliary agents are considered as a promising strategy for the administration of various challenging drugs including peptides, proteins and oligosaccharides therapeutics. The delivery of such therapeutics is hampered due to rapid degradation, restricted uptake, short residence time, poor solubility and limited half-life. The recent emergence of nanomedicine based on bio/mucoadhesive auxiliary agents is offering new avenues to overcome these drawbacks. Hence, it is important to understand the mechanism of nanoscale bio/mucoadhesion, protocols for investigating bio/mucoadhesive potential at nanoscale. This chapter is an endeavor to focus on the mechanism of bio adhesion and the bio/mucoadhesive auxiliary agents that are used in the design of the targeted oral, nasal, ocular, vaginal, and buccal nanomedicine with their properties that affect the bio/mucoadhesion.

    Bio Adhesion, Mucoadhesion, Nano Cargoes, Polymers, Targeted Drug Delivery System

    (1) Ali Iqbal
    M.Phil Candidate, Department of Life Sciences, Faculty of Pharmacy, University of Hertfordshire, Hatfield, United Kingdom UK.
    (2) Ramsha Malik
    M. Phil Candidate, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (3) Malik Irfan Zulfiqar
    BS Biotechnology Scholar, Department of Biological Sciences, International Islamic University, Islamabad, Pakistan.
    (4) Maria Hassan Kiani
    PhD Candidate, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
    (5) Muhammad Rauf ul Hassan
    Associate Professor, Department of Pulmonology, Quaid-i-Azam Medical College, Bahawalpur Victoria Hospital, Bahawalpur, Punjab, Pakistan.
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Cite this article

APA

CHICAGO

    CHICAGO : Iqbal, Ali, Ramsha Malik, and Malik Irfan Zulfiqar. 2019. "Bio-Adhesive Nanomedicine for Targeted Drug Delivery." Global Drug Design & Development Review, IV (I): 10-23 doi: 10.31703/gdddr.2019(IV-I).02

HARVARD

    HARVARD : IQBAL, A., MALIK, R. & ZULFIQAR, M. I. 2019. Bio-Adhesive Nanomedicine for Targeted Drug Delivery. Global Drug Design & Development Review, IV, 10-23.

MHRA

    MHRA : Iqbal, Ali, Ramsha Malik, and Malik Irfan Zulfiqar. 2019. "Bio-Adhesive Nanomedicine for Targeted Drug Delivery." Global Drug Design & Development Review, IV: 10-23

MLA

    MLA : Iqbal, Ali, Ramsha Malik, and Malik Irfan Zulfiqar. "Bio-Adhesive Nanomedicine for Targeted Drug Delivery." Global Drug Design & Development Review, IV.I (2019): 10-23 Print.

OXFORD

    OXFORD : Iqbal, Ali, Malik, Ramsha, and Zulfiqar, Malik Irfan (2019), "Bio-Adhesive Nanomedicine for Targeted Drug Delivery", Global Drug Design & Development Review, IV (I), 10-23

TURABIAN

    TURABIAN : Iqbal, Ali, Ramsha Malik, and Malik Irfan Zulfiqar. "Bio-Adhesive Nanomedicine for Targeted Drug Delivery." Global Drug Design & Development Review IV, no. I (2019): 10-23. https://doi.org/10.31703/gdddr.2019(IV-I).02